论文部分内容阅读
目的总结不同类型小儿癫持续状态(SE)的临床、脑电图特点及治疗反应,提高诊断及治疗水平。方法对36例临床发作及脑电图监测符合SE的患儿按发作类型进行分类,分析不同类型发作特点、病因、脑电图变化及治疗反应。结果症状性癫19例,隐源性癫14例,特发性癫3例。既往SE史14例,4例为首次发作。10例发病前智力、运动发育落后,5例发病后倒退。12例诊断为癫综合征。不同发作类型脑电图改变不同。非惊厥性癫持续状态(NCSE)患儿脑电图均表现为背景活动差,慢波多,其中4例伴有睡眠中癫性电持续状态。12例给予氯硝西泮,11例有效控制。结论不同类型的SE发作形式及脑电图表现不同,NCSE更为复杂,早期诊断和处理可提高生存率,减少神经后遗症的发生。
Objective To summarize the clinical, electroencephalographic features and response of different types of children with epileptic seizures (SE) and to improve their diagnosis and treatment. Methods According to the types of seizures, 36 cases with clinical seizure and EEG monitoring conforming to SE were divided into different types of seizures, etiology, EEG changes and treatment responses. Results 19 cases of symptomatic epilepsy, cryptogenic epilepsy in 14 cases, idiopathic epilepsy in 3 cases. 14 cases of previous history of SE, 4 cases for the first episode. 10 cases of pre-onset intelligence, motor development lagging behind, 5 cases retrograde onset. 12 cases diagnosed as epilepsy syndrome. Different types of seizures EEG changes. EEG in non-convulsive status epilepticus (NCSE) patients showed poor background activity and slow wave amplitude, and 4 of them were associated with sleep-induced epileptic seizures. 12 cases were given clonazepam, 11 cases of effective control. Conclusion Different types of SE seizures and different EEG manifestations, NCSE is more complicated, early diagnosis and treatment can improve the survival rate and reduce the occurrence of neurological sequelae.