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本文回顾性分析３６例精神分裂症或偏执性精神障碍住院自杀病人的精神药物治疗、既往病史及有关精神症状资料，并与同期住院的３６例匹配对照者进行比较。结果显示，自杀组的既往自杀未遂次数、抑郁症状及阴性症状项目数明显多于对照组；而抗精神病药（ＡＰＤ）剂量则显著低于对照组。逐步Ｌｏｇｉｓｔｉｃ回归分析结果提示，抑郁症状、阴性症状及低ＡＰＤ剂量是精神分裂症或偏执性精神障碍自杀病人的三个非依赖性危险因素。
This retrospective analysis of 36 patients with schizophrenia or paranoid mental disorder hospital suicide psychotropic drug treatment, previous medical history and information on mental symptoms, and with the same period of hospitalized 36 matched controls were compared. The results showed that the number of suicide attempts, the number of depression symptoms and negative symptoms in suicide group were significantly more than those in control group, while the dose of antipsychotic drugs (APD) was significantly lower than that in control group. Logistic regression analysis showed that depression, negative symptoms and low APD dose were three independent risk factors for suicide in schizophrenia or paranoid disorder.