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我们曾报导了恶性肿瘤病变对肝脏、肌肉组织中溶酶体酶(lysosomale enzymes)活性的影响,发现未转移的肾癌患者肝组织中的芳硫酯酶(arylsulphatase)β-葡萄糖醛酸酶(β-glucuronidase 和组织蛋白酶 D(cathepsin-D)活性升高,组织蛋白酶 D 在各类肿瘤患者的肌组织中均见上升。肝脏肌肉组织中的这些水解酶的活性升高一般意味着癌变时溶酶体酶的释放增加了,因此有理由认为,癌患者中的这些酶或至少是其中某些酶在血中浓度比无癌者高,实
We have reported the effect of malignant tumor lesions on the activity of lysosomale enzymes in the liver and muscle tissues and found that arylsulphatase β-glucuronidase in the liver tissue of patients with non-metastatic kidney cancer ( The activity of β-glucuronidase and cathepsin-D increases, and cathepsin D increases in muscle tissue of various tumor patients.The increase in the activity of these hydrolases in the liver muscle tissue generally means that cancerous time dissolves. The release of enzymes has increased, so it is reasonable to believe that in cancer patients, these enzymes or at least some of them have higher blood concentrations than those without cancer.