Horner-Emmons反应在各类烯烃的台成中得到广泛应用,但通过该反应制备卤代烯烃的报导却相对较少。 Bergmann、Zimmer和山口彰宏等曾先后报导了氟苄基膦酸二乙酯、对硝基氯苄基膦酸二苯醋以及对硝基溴或碘苄基膦酸二乙酯与芳香醛的反应,但反应中均使用了较强的碱,如RLi、NaH和NaOR。近年来,将季铵盐和冠醚用于Horner-Emmons反 The Horner-Emmons reaction is widely used in the synthesis of various types of olefins, but reports of the production of haloolefins by this reaction are relatively rare. Bergmann, Zimmer and Yamaguchi Akihiro et al. Have reported successively the reaction of diethyl fluorobenzylphosphonate, p-nitrobenzylphosphonic acid diphenyl ether and diethyl p-nitrobromide or iodobenzylphosphonate with aromatic aldehydes , But stronger bases such as RLi, NaH and NaOR were used in the reaction. In recent years, quaternary ammonium salts and crown ethers have been used for Horner-Emmons counter