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近来许多报道发现,临床上对中风患者抑郁状态进行的针对性治疗往往可明显提高患者运动功能的恢复,其中以5-HT激动剂类抗抑郁药作用较为明显[1-2]。抗抑郁治疗促进运动功能恢复的机理目前还不清楚,由于脑中风后运动障碍除与皮质运动神经元缺失及神经通路的破坏有关?
Recently, many reports found that targeted treatment of stroke in patients with depression often can significantly improve the recovery of motor function, in which 5-HT agonist antidepressant effect is more obvious [1-2]. Antidepressant therapy to promote the recovery of motor function is still not clear, because of stroke in addition to motor cortex and motor cortex neuronal loss and the destruction of neural pathways?