胆道闭锁(Biliary Atresia BA)是引起3个月以内小儿阻塞性黄疸的主要原因,也是造成婴幼儿死亡的重要肝脏疾病。在东方国家,其发病率约为1:6000￣10000。胆道闭锁的病因病理尚未完全明了,目前认为主要与病毒感染及免疫异常有关。然而,临床资料显示,部分BA患儿存在胆管板畸形或胰 Biliary Atresia BA is the main cause of obstructive jaundice in children within 3 months and is also an important liver disease causing infants and young children to die. In the eastern countries, the incidence of about 1: 6000 ~ 10000. The etiology and pathogenesis of biliary atresia is not yet fully understood, and is currently mainly associated with viral infection and immune abnormalities. However, clinical data show that some BA children with biliary abnormalities or pancreas