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目的观察羟苯磺酸钙联合复方肾衰汤治疗慢性肾脏病的疗效。方法44例慢性肾脏病患者给予羟苯磺酸钙和复方肾衰汤联合治疗4周,观察治疗前后肾功能、血尿酸、血象、肝功能及尿常规变化。结果与治疗前比较,口服羟苯磺酸钙和复方肾衰汤后,血肌酐与血尿酸1周开始下降,持续降低至4周(P<0.01);血尿素在4周降低(P<0.01);治疗期间患者血象、肝功能及尿蛋白无改变(P>0.05)。结论羟苯磺酸钙联合复方肾衰汤能够延缓慢性肾功能不全的进展。
Objective To observe the effect of calcium dobesilate combined with compound kidney decoction on chronic kidney disease. Methods Forty - four patients with chronic kidney disease were treated with combination of calcium dobesilate and compound rennin decoction for 4 weeks. The changes of renal function, serum uric acid, blood, liver function and urine before and after treatment were observed. Results Compared with those before treatment, serum creatinine and serum uric acid began to decline in one week after oral administration of calcium dobesilate and compound renal failure decoction, and continued to decrease to 4 weeks (P <0.01); blood urea decreased at 4 weeks (P <0.01) ); During treatment, there was no change in blood, liver function and urine protein (P> 0.05). Conclusion Calcium dobesilate combined with compound renal decoction can delay the progress of chronic renal insufficiency.