本文介绍一种对菌斑和牙龈健康有效的含有枸橼酸锌和非阳离子杀菌剂三氯苯氧氯酚(triclosan)牙膏。枸橼酸锌有抗菌斑特性且与现代牙膏中的正常成份是相容的。三氯苯氧氯酚在体外对革兰氏阳性和阴性微生物具有良好作用。材料和方法:试验牙膏含有氢氧化铝,单氟磷酸钠,阴离子表面活性剂,0.5％或1.0％三氢氧化枸橼酸锌(Zinc Citrate Trihydrate)晶体和0.2％,0.5％或0.6％的三氯苯氧氯酚。安慰牙膏中除不含枸橼酸锌和三氯苯氧氯酚外,其他成份完全相同。20名男性和29名女性,年龄23～55岁的患者参加本研究。研究分两部份即4周的研究前期(以减少诱导和专门洁治的影响)和10周实验期。后者又分为两个4周,其中间隔两周。实 This article describes a triclosan toothpaste containing zinc citrate and a non-cationic bactericide that is both healthy and effective against plaque and gums. Zinc citrate has anti-plaque properties and is compatible with the normal ingredients of modern toothpastes. Triclosan has a good effect on Gram-positive and -negative microorganisms in vitro. Materials and Methods: The test toothpaste contains aluminum hydroxide, sodium monofluorophosphate, anionic surfactant, 0.5% or 1.0% zinc citrate trihydrate crystals and 0.2%, 0.5% or 0.6% tris Chlorophenol. In addition to toothpaste does not contain zinc citrate and triclosan, the other ingredients are identical. Twenty men and 29 women aged 23 to 55 years participated in this study. The study was divided into two parts: a 4-week pre-study (to reduce the effects of induction and specialized clean-up) and a 10-week study. The latter is divided into two four weeks, two weeks apart. real