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核素肝胆显像结合十二指肠引流液胆红素含量测定,为婴儿黄疸提供更有效的鉴别诊断方法。33例婴儿黄疸患儿均经手术、术中肝活检及临床随访证实,行(99m)~Tc-亚氨基二乙酸(EHIDA)肝胆显像和十二指肠引流液胆红素含量测定。(99m)~Tc-EHIDA 肝胆显像诊断胆道闭锁的敏感性为100%,特异性为72.7%。十二指肠引流液胆红素含量测定则分别为100%和94.45%。核素肝胆显像方法灵敏、简单、安全、无创伤,对肠道不显影患儿再行十二指肠引流液胆红素含量测定,可提高诊断的特异性。
Radionuclide hepatobiliary imaging combined with determination of bilirubin content of duodenal drainage fluid, to provide a more effective differential diagnosis of infant jaundice. Thirty-three infants with jaundice were confirmed by operation, intraoperative liver biopsy and clinical follow-up. The levels of 99m Tc-Iminodiacetic acid (EHIDA) hepatobiliary imaging and bilirubin in duodenal drainage fluid were determined. (99m) ~ Tc-EHIDA hepatobiliary imaging diagnosis of biliary atresia sensitivity was 100%, specificity was 72.7%. Determination of bilirubin content of duodenal drainage fluid were 100% and 94.45%. Radionuclide hepatobiliary imaging method is sensitive, simple, safe and noninvasive, and the determination of bilirubin in the duodenal drainage fluid in children with no intestinal development can improve the diagnostic specificity.