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胎盘是母体与胎儿间进行物质交换的器官。胎儿在子宫中发育,依靠胎盘从母体获取营养。氨基酸作为蛋白质的组成成分以及非蛋白物质(例如NO、多胺、核苷酸和神经递质等)合成的重要前体,是一种必需的营养成分,在胎儿的生长发育过程中发挥着至关重要的作用〔1〕。由氨基酸转运体介导的氨基酸跨胎盘转运是供给胎儿能量的重要途径之一,对维持胎儿的存活和胎儿在子宫内的正常生长发育起着关键性的作用。
Placenta is the body and fetus for the exchange of material between the organs. Fetal development in the womb, rely on the placenta to obtain nutrition from the mother. Amino acids, as an integral part of proteins and important precursors for the synthesis of non-proteinaceous substances (such as NO, polyamines, nucleotides and neurotransmitters, etc.), are essential nutrients that act during fetal growth and development The crucial role [1]. Amino acid transporter-mediated amino acid transplacental transport is one of the important ways to supply fetal energy, which plays a key role in maintaining fetal survival and normal fetal growth in the uterus.