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目的:比较非洛地平缓释片与苯那普利的降压疗效.方法:130例原发性高血压患者随机分为非洛地平缓释片组(F组)与苯那普利组(B组),123例完成治疗.结果:降压幅度F组均高于B组,但差异尤显著性(P＞0.05).2周后F组与B组的降压总有效率为66.7％、48.7％;4周后降压总有效率为87.3％、68.3％.两组比较均有显著性差异(P＜0.05).两药不良反应均较少.结论:两药均为有效、耐受性好的降压药,而在降压效果方面非洛地平缓释片5~10mg/d优于苯那普利10~20mg/d.“,”Aim: to compare the efficacy of Felodipine - ER with that of Bezanapril. Method: ahundred and thirty patients with essential hypertension were randomly divided into Felodipine - ER group(F group) and Bezanpril group (B group). 123 patients completed the study. Result: alI the reductionof BP in F group was more than that in B group. But the difference between two groups wasn\' t statisti-cally significant (P >0. 05). After 2 weeks, the total effective rate in F group was 66. 7%, whereasit in B group was 48. 7% (P <0.05). After 4 weeks, the total effective rate was 87. 3% and 68.3% respectively (P <0.05). The inciclance of adverse effects was lower and adveres effects were mild.Condusion: both Felodipine - ER and Bezanapril are effective and well toleraled in freating the essential hy-pertension. However, Felodipine - ER 5 ~ 10mg/d is more effective than Bezanapril 10~ 20mg/d in con-troling high blood pressure.