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[目的]了解医学院临床医学专业新生抑郁与自杀意念的发生率及其两者之间的关系，为有效干预自杀意念，预防自杀行为提供依据。[方法]整群随机抽样的方法抽取某医学院340名临床医学专业的新生，采用抑郁自评量表（SDS）和自杀意念自评量表（SIOSS）调查学生抑郁及自杀意念现状。[结果]该医学院临床医学专业新生抑郁的发生率为31．76％，自杀意念发生率为8．82％，有无抑郁新生的自杀意念发生率存在显著性差异（P ＜0．05），抑郁与自杀意念呈显著正相关（P ＜0．05），有无自杀意念新生的自杀意念各因子及抑郁特异性症状存在显著性差异（ P ＜0．05）。[结论]该医学院临床医学专业部分新生存在一定程度的抑郁及自杀意念，抑郁与自杀意念两者之间存在显著相关性。“,”[Objective]To understand the incidence of depression and suicide ideation among freshmen ma-joring in clinical medicine at a medical college and their correlation so as to provide the basis for effectively in-tervening suicide ideation and preventing suicide .[Methods] Random cluster sample method was used to choose 340 freshmen majoring in clinical medicine at a medical college .The status quo of depression and suicide ideation were investigated by self-rating depression scale(SDS) and self-rating idea of suicide scale (SIOSS) .[Results]The incidence of depression and suicide ideation in freshmen majoring in clinical medicine at the medi-cal college was 31 .76% and 8 .82% ,respectively .There were significant differences in the incidence of depres-sion among freshmen with and without suicide ideation ( P <0 .05) .Depression showed significantly positive correlation with suicide ideation ( P <0 .05) .There were significant differences in the factors of suicide idea-tion and special symptoms of depression among freshmen with and without suicide ideation ( P<0 .05) .[Con-clusion] Freshmen majoring in clinical medicine at the medical college have certain depression and suicide idea-tion .There is significant correlation between depression and suicidal ideation .