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目的从几组化疗止吐剂中筛选一帖经济有效、便于推广应用的抗癌止吐处方。方法胃复安为对照组;利多卡因、恩丹西酮、综合防治用药为观察组进行自身前、后对照,以止吐效果为主要指标的多侧面观察比较。结果急性期和延迟期消化道反应防治(0°-Ⅰ°,下同)有效率分别是:胃复安34%、28%;利多卡因82%、X%;恩丹西酮88%、84%;综合防治用药94%、100%。结论以安定、地塞米松、胃复安联合按需用药是较理想的抗癌化疗止吐处方。
Aim To screen one anti-cancer antiemetic prescription which is cost-effective and easy to popularize and apply from several groups of chemotherapy antiemetics. Methods metoclopramide as the control group; lidocaine, ondansetron, comprehensive prevention and treatment for the observation group before and after the control, antiemetic effect as the main indicators of multi-lateral comparison. Results Acute and delayed response to digestive tract reactions (0 ° -Ⅰ °, the same below) the effective rates are: metoclopramide 34%, 28%; lidocaine 82%, X%; ondansetron 88% 84%; comprehensive prevention and treatment of drug 94%, 100%. Conclusions Combination of diazepam, dexamethasone and metoclopramide on demand is an ideal anticancer chemotherapy antiemetic prescription.