多发性硬化(下称MS)的特点是神经系统的多发性病灶反复发作与缓解,且症状与体征复杂多变。据我们观察,本病发生皮肤搔痒症状者并不少见,但国内外文献对此报告较少。本病的搔痒症状常表现为“奇痒”,可发生于MS的不同病期。当奇痒为首发症状时,本病多被误诊为皮肤病或神经官能症。本文报告14例具有奇痒症状的MS,并探讨其某些规律,以供同道参考。 Multiple sclerosis (MS) is characterized by repeated episodes and remissions of multiple lesions of the nervous system with complicated and variable symptoms and signs. According to our observation, it is not uncommon for patients with this disease to experience pruritus, but there are few reports from domestic and foreign literatures. The symptoms of this disease often manifested as “itching”, can occur in different stages of MS. When the itching is the first symptom, the disease is often misdiagnosed as dermatosis or neurosis. This article reports 14 cases of itching symptoms MS, and explore some of its laws for fellow reference.