目的探讨超声联合胎儿纤维连接蛋白预测早产的临床价值。方法对醴陵市妇幼保健院2013年5月至2014年12月收治的114例有先兆早产症状的孕妇分别进行超声宫颈长度(CL)及宫颈分泌物胎儿纤维连接蛋白(f FN)检测,追踪妊娠结果,比较CL、f FN单独检测与联合检测对早产的预测价值。结果本研究114例孕妇中早产62例(54.39%),CL≤30 mm早产率为70.27%,f FN(+)早产率为70.24%,分别明显高于CL>30 mm及f FN(-)孕妇。CL≤30 mm且f FN(+)早产率为98.15%。CL联合f FN检测的特异度、阳性预测值分别为98.08%、98.15%,均明显高于单独检测组(P<0.01)。结论超声联合胎儿纤维连接蛋白检测可提高对早产的阳性预测值,对联合检测结果为阳性的孕妇应给予及时干预,以改善妊娠结局。 Objective To investigate the clinical value of ultrasound combined with fetal fibronectin in predicting preterm delivery. Methods 114 pregnant women with symptoms of threatened preterm labor who were treated in Liling City MCH from May 2013 to December 2014 were examined with ultrasound cervical length (CL) and cervical secretions fetal fibronectin (F FN) Results, compared CL, f FN single detection and combined detection of the predictive value of preterm birth. Results The preterm delivery of 114 pregnant women was 62 (54.39%). The premature delivery rate was 70.27% with CL≤30 mm and 70.24% with f FN (+) preterm delivery, which were significantly higher than those with CL> 30 mm and f FN (- Pregnant women. CL ≤ 30 mm and f FN (+) premature delivery was 98.15%. The specificity and positive predictive value of CL combined with f FN detection were 98.08% and 98.15%, respectively, which were significantly higher than those of the single test group (P <0.01). Conclusion Ultrasound combined with detection of fetal fibronectin can increase the positive predictive value of preterm birth. Pregnant women who are positive for combined detection should be given timely intervention to improve pregnancy outcome.