论文部分内容阅读
近十多年来在抗瘧药物的研究中,出现了数种新的有效药物。这些药物不论疗效、毒性、用法等方面都远胜于已知的常用抗瘧药物,这对瘧疾的防治起了莫大的作用。只因这些药物在国内有的还没有普遍服用,有的尚属初次试用,有关它们的性能和服用方法,以及对我国瘧疾的疗效如何,尚不太熟知,兹仅凭作者所知的文献资料和自己的经验,简要的介绍如下。为了更好的了解这数种药物的性能和使用方法,首先必须说明下列几点,以为讨论的基础。(一)瘧疾复发机转的解说:傅染性的媒介按蚊叮刺入体后,瘧原虫胞子体随血流半小时左右即至肝脏,鑽入肝实质细胞,进行裂体增殖,产生无数的组织期裂殖子,瘧原虫发育至此时统称为前期血球外型。这些裂殖子鑽入红血球,开始血球内型的生活史。而一部分裂殖子(恶性瘧除外)又鑽入
In the past ten years in the study of anti-malarial drugs, there have been several new and effective drugs. Regardless of efficacy, toxicity and usage, these drugs are much better than the known commonly used anti-malarial drugs, which play a great role in the prevention and treatment of malaria. It is only because of the fact that some of these drugs have not yet been commonly used in the country and some are still being tested for the first time. Their performance and methods of taking them, and the efficacy of malaria in our country, are not yet well known. And their own experience, a brief introduction is as follows. In order to better understand the performance and use of these drugs, we must first explain the following points to serve as the basis for the discussion. (A) malaria relapse mechanism explanation: Fu sexually transmitted mosquito bites into the body, the malaria parasite blood flow about half an hour or even the liver, into the liver parenchymal cells, proliferation of Rift, resulting in numerous The organization of merozoites, Plasmodium development so far collectively referred to as pre-blood cell appearance. These merozoites drill into the red blood cells and start the life cycle of the blood type. And part of merozoites (except for falciparum malaria) and drilling