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取20例坐高85mm～240mm的胎儿胰腺,按头、体、尾分别取材。组织学观察显示胰腺实质被结缔组织分割成叶或小叶,腺泡分化逐渐清晰,但基底部嗜碱性不明显,提示其外分泌功能还很弱。少量聚集的内分泌细胞与外分泌部细胞无明显界限。仅见较大量聚集成团的内分必细胞外有结缔组织包绕,易与外分泌部区别。免疫组织化学染色显示胰岛内B细胞,各小叶间、叶间B细胞数目差别显著,而同一胰腺的头、体、尾部B细胞数目无明显差异。提示:本研究对临床进行胎儿胰岛移植提供了形态学依据。
Take 20 cases of sitting height 85mm ~ 240mm fetal pancreas, according to the head, body, tail were drawn. Histological observation showed that the parenchyma of the pancreas was divided into the leaf or the lobule by the connective tissue. The acinar differentiation gradually became clear, but basal basophilicity was not obvious, suggesting that the exocrine function was weak. A small amount of aggregated endocrine cells and exocrine cells without obvious boundaries. Only see a large number of clusters into groups within the extracellular extracellular connective tissue around, easy to distinguish with the exocrine Department. Immunohistochemical staining showed that there were significant differences in the number of B cells among the islet cells, among the interlobular lobes and between the leaves, while there was no significant difference in the number of B cells between the head, tail and tail of the same pancreas. Tip: This study provides a morphological basis for the clinical transplantation of fetal islets.