论文部分内容阅读
目的了解广东云浮地区急性呼吸道感染(ARI)常见病毒流行病学特点,为临床诊断、治疗及防控提供线索和依据。方法收集2014年1月至2015年12月在我院就诊的2 193例急性呼吸道感染患者鼻咽部拭子标本,采用直接免疫荧光法检测甲型流感病毒(IFA)、乙型流感病毒(IFB)、副流感病毒Ⅰ(PIV1)、副流感病毒Ⅱ(PIV2)、副流感病毒Ⅲ(PIV3)、呼吸道合胞病毒(RSV)、腺病毒(ADV)7种常见呼吸道病毒感染情况,并进行统计学分析。结果 2 193例标本中,检出呼吸道病毒阳性标本382例(17.42%),其中RSV阳性率最高,为12.18%(267/2 193),其次为IFA(1.37%)和PIV3(1.37%)。不同年龄呼吸道病毒检出率不同,0~月、6~月患儿检出率较高,分别为25.27%和21.26%。不同季节呼吸道病毒检出率不同,冬天最高为30.47%,其次为春天(18.4%),且各季节最主要检出病毒均为RSV。结论2014年1月至2015年12月,云浮地区儿童急性呼吸道感染最主要病毒病原体为RSV,且易在1岁以下婴幼儿中流行,好发于冬春季;随着年龄增长,总体病毒检出率下降,且呈一定的季节性流行。
Objective To understand the epidemiological characteristics of common ARI virus in Yunfu area of Guangdong Province and provide clues and evidences for clinical diagnosis, treatment and prevention. Methods Nasopharyngeal swab specimens from 2 193 patients with acute respiratory infection who were treated in our hospital from January 2014 to December 2015 were collected. The IFA, IFB and IFB were detected by direct immunofluorescence assay. (PIV1), parainfluenza virus (PIV2), parainfluenza virus (PIV3), respiratory syncytial virus (RSV) and adenovirus (ADV) Analysis. Results Of the 2 193 samples, 382 (17.42%) were positive samples of respiratory viruses. The positive rate of RSV was 12.18% (267/2 193), followed by IFA (1.37%) and PIV3 (1.37%). The detection rates of respiratory viruses at different ages were different, and the detection rates were higher in 0 ~ month and 6 ~ month, which were 25.27% and 21.26% respectively. The detection rates of respiratory viruses were different in different seasons, the highest was 30.47% in winter and the second was in spring (18.4%), and the most important virus in all seasons was RSV. Conclusion From January 2014 to December 2015, the most common viral pathogen of acute respiratory infection in children in Yunfu was RSV, and was predisposed to infants under 1 year old, which occurred in winter and spring. With the increase of age, the total virus was detected The rate of decline, and showed a certain seasonal epidemic.