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目的研究丹红注射液联合低分子肝素治疗不稳定性心绞痛的疗效。方法 88例不稳定性心绞痛患者随机分为两组:对照组43例,给予常规扩冠、抗栓、调脂等治疗;观察组45例,在上述常规治疗基础上加用丹红注射液20 ml静滴,1次/d,低分子肝素针5 ml皮下注射,12 h/次,10 d为1个疗程。治疗期间观察并记录患者心绞痛发作频率、疼痛程度,及心电图ST-T改善情况,采用χ2检验,比较分析两组对象临床有效率及心电图有效率。P<0.05为差异有统计学意义。结果 1临床症状方面,观察组总有效率为95.56%,对照组为79.07%,两组差异有统计学意义(P<0.05);2心电图改善情况,观察组总有效率为91.11%,对照组为72.09%,两组差异有统计学意义(P<0.05)。结论丹红联合低分子肝素治疗不稳定性心绞痛疗效肯定,值得临床推广。
Objective To study the efficacy of Danhong injection combined with low molecular weight heparin in the treatment of unstable angina pectoris. Methods 88 patients with unstable angina pectoris were randomly divided into two groups: control group, 43 cases, given conventional crown expansion, antithrombotic, lipid-lowering treatment; observation group of 45 cases, based on the above conventional treatment with Danhong injection 20 ml intravenous infusion, 1 time / d, low molecular weight heparin needle 5 ml subcutaneous injection, 12 h / time, 10 d for a course of treatment. The duration of angina pectoris, the degree of pain and the ST-T improvement of electrocardiogram were observed and recorded during the treatment. The χ2 test was used to compare the clinical efficacy and the efficiency of electrocardiogram in both groups. P <0.05 for the difference was statistically significant. Results 1 The clinical symptoms, the observation group the total effective rate was 95.56%, the control group was 79.07%, the difference between the two groups was statistically significant (P <0.05); 2 ECG improvement, the observation group the total effective rate was 91.11% 72.09%, the difference between the two groups was statistically significant (P <0.05). Conclusion Danhong combined with low molecular weight heparin for the treatment of unstable angina pectoris is worthy of clinical promotion.