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目的 评价食管静脉曲张出血硬化治疗疗效。方法 对我院 1987年 4月至 2 0 0 0年 5月行食管静脉曲张硬化治疗 (EVS)的 10 10例门脉高压食管静脉曲张出血患者 ,进行回顾分析。肝硬化患者 85 0例 ,肝癌 16 0例 ,共行EVS 32 0 3例次 ,急诊 6 0 2例次 ,择期 2 6 0 1例次 ,追加治疗 5 0 2例次 ,710例肝硬化患者首次进行EVS(3.18± 1.1)次 ,对 5 79例肝硬化患者进行了 3～ 15 7个月的随访 ,平均随访时间为 (4 2 .47± 32 .78)个月。肝硬化患者 85 0例 ,其中治疗结束时 70 6例行胃镜检查。结果 1.全组急诊止血率为 97.0 % ,治疗并发症为 13.4% ,死亡率为 1.8%。 2 .肝硬化患者食管静脉曲张消失和基本消失率为 84.1% ,远期再发出血率为 2 3.7% ,生存率按Kaplan Meier法计算 ,1、3、5、10年分别为 (95 .8± 0 .8) %、(86 .1± 1.6 ) %、(74.5± 2 .4) %和 (5 3.6± 3.8) %。结论 EVS对食管静脉曲张出血仍是一重要治疗方法。
Objective To evaluate the therapeutic effect of esophageal variceal hemorrhage sclerosis. Methods A retrospective analysis was performed on 10 10 patients with esophageal varices of portal hypertension who underwent esophageal variceal sclerosis (EVS) between April 1987 and May 2000 in our hospital. There were 85 0 cirrhotic patients and 160 liver cancer patients, with a total of 32 0 EVS cases, 622 emergency cases and 2601 elective patients, with additional treatment of 502 cases and 710 cirrhosis patients for the first time The EVS (3.18 ± 1.1) times were followed up for 3 to 157 months in 5 79 patients with cirrhosis. The mean follow-up time was (4 2 .47 ± 32 .78) months. 85 0 patients with cirrhosis, including 706 endoscopy at the end of treatment. The results showed that the overall emergency treatment rate was 97.0%, the complication rate was 13.4% and the mortality rate was 1.8%. The disappearance and disappearance rate of esophageal varices in patients with cirrhosis was 84.1%, and the recurrence rate was 23.7%. The survival rate was calculated according to Kaplan Meier method. The rates of esophageal varices were (95.8 ± 0 .8%, (86.1 ± 1.6)%, (74.5 ± 2 .4)% and (53.6 ± 3.8)%, respectively. Conclusion EVS is still an important treatment for esophageal variceal bleeding.