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目的 探讨脑转移瘤 (BM)的诊断和治疗方法。方法 采用CT、MRI诊断BM 62例 ,其中 8例术前误诊。 47例单发BM全切 ,15例多发BM行大瘤切除。术后 5 5例行综合治疗。结果 本组 5 5例生存至少半年。 3 5例随访 8个月至6年半 ,存活期 8～ 75个月 ,平均 2 7个月。其中手术加放疗组 ,平均存活 11个月 ;手术加放疗及化疗组 ,平均存活 2 9个月 ;手术加γ 刀及化疗组 ,平均存活 14个月。未查到原发灶的单发BM组 ,平均存活 3年 ;有明确原发灶及多发BM ,平均存活14个月。术后死亡 7/62。结论 对有手术适应证的BM ,积极手术治疗 ,术后综合治疗能延长BM生存期 ,最佳治疗方案为手术加放疗和化疗。
Objective To investigate the diagnosis and treatment of brain metastases (BM). Methods CT and MRI were used to diagnose 62 cases of BM, of which 8 cases were misdiagnosed preoperatively. 47 cases of single BM complete resection, 15 cases of multiple BM line excision. Postoperative 5 5 routine comprehensive treatment. Results This group of 55 patients survived for at least six months. 35 cases were followed up for 8 months to 6 and a half years, with a survival of 8 to 75 months, an average of 27 months. The operation and radiotherapy group, the average survival of 11 months; surgery plus radiotherapy and chemotherapy group, the average survival 29 months; surgery plus γ knife and chemotherapy group, the average survival of 14 months. Not found in the primary tumor of single BM group, the average survival of 3 years; a clear primary tumor and multiple BM, the average survival of 14 months. Postoperative death 7/62. Conclusion For active BM with active indications, BM can prolong the survival of patients with BM. The best treatment is surgery plus radiotherapy and chemotherapy.