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曾从中药灵芝中分得许多羊毛甾烷型三萜类化合物,其中从试管培养的菌丝体中分得的一些化合物对肝癌细胞具细胞毒作用。作者发现灵芝子实体的氯仿粗提取物对培养的肝癌细胞中醌氧化还原酶(QR)的活性具有诱导作用。
A lot of lanostane triterpenoids were isolated from Ganoderma lucidum, and some of the compounds isolated from test tube cultured mycelia had cytotoxic effects on HCC cells. The authors found that crude chloroform extract of Ganoderma lucidum fruiting body has an inducing effect on the activity of quinone oxidoreductase (QR) in cultured hepatoma cells.