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用放免法对90例Ⅰ～Ⅱ级急性梗阻性喉气管炎(ASLT)患儿的ACTH、皮质醇、cAMP及cGMP行动态观察。结果Ⅰ级患儿入院时ACTH水平升高,超过对照组4.8倍,而皮质醇仅增高3.7%;治愈后ACTH降低,但未达正常;Ⅱ级患儿ACTH和皮质醇均明显增高,治愈后降,低,未达正常。61例患儿环核苷酸(cN)检查Ⅰ级患儿仅cAMP升高,而cGMP正常;Ⅱ级患儿cAMP和cGMP均升高,治愈后下降。证实ASLT患儿有应激系统变化,其程度取决于病情,梗阻解除后ACTH和皮质醇浓度虽降低,但未达正常值。cN系统参与了ASLT的发生和经过,不同
The dynamic observation of ACTH, cortisol, cAMP and cGMP in 90 cases of Ⅰ ~ Ⅱ acute obstructive laryngotracheitis (ASLT) children by radioimmunity. Results The level of ACTH in children with grade Ⅰ increased 4.8 times more than that in control group, while the cortisol level increased only 3.7%. After treatment, the ACTH level decreased but did not reach the normal level. The levels of ACTH and cortisol in grade Ⅱ children were significantly higher than those in control group Lower, lower, lower than normal. The cAMP and cGMP levels of 61 children with grade Ⅰ were only elevated cAMP, but cGMP was normal. Confirmed that children with ASLT have stress system changes, the extent depends on the condition, although the ACTH and cortisol concentrations after the obstruction was relieved, but not up to normal. cN system involved in the occurrence and after ASLT, different