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目的:观察米索前列醇对第三产程的影响和预防产后出血的效果。方法:选择2001年1月～2002年1月间150例产妇,孕周均在37～42周,单胎头位、无妊娠合并症及并发症。A组90例,服用米索前列醇;B组60例宫体注射催产素10U,观察第三产程时间及阴道出血量,准确测量并记录。结果:A组第三产程平均6～12min,产后出血1例;B组第三产程平均8～20min,产后出血3例。A组第三产程明显短于B组,产后出血量有所减少,产后出血发生率较B组低。A组出现较轻的全身性反应,其中恶心3例,腹泻2例,头痛1例,均于2h内恢复正常。结论:第三产程的长短直接影响产后出血量,及时应用米索前列醇是预防产后出血的有效手段。
Objective: To observe the effect of misoprostol on the third stage of labor and the effect of preventing postpartum hemorrhage. Methods: 150 maternal women from January 2001 to January 2002 were selected. The gestational age ranged from 37 to 42 weeks. The single fetus had no pregnancy complications and complications. A group of 90 patients, taking misoprostol; B group 60 cases of oxytocin injection of uterine body 10U, observation of the third stage of labor time and vaginal bleeding, accurate measurement and record. Results: The average length of the third stage of labor in group A was 6 ~ 12min and the rate of postpartum hemorrhage in group A was 3. The average length of the third stage of labor in group B was 8 ~ 20min. Postpartum hemorrhage occurred in 3 cases. A group of the third stage of labor was significantly shorter than the B group, postpartum hemorrhage decreased, the incidence of postpartum hemorrhage than the B group. Group A showed a mild systemic reaction, of which nausea in 3 cases, diarrhea in 2 cases, headache in 1 case, were returned to normal within 2h. Conclusion: The length of the third stage of labor directly affects the amount of postpartum hemorrhage. The timely application of misoprostol is an effective way to prevent postpartum hemorrhage.