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目的观察序贯性血液净化在治疗重度毒鼠强中毒方面的临床疗效。方法选择我院收治27例重度毒鼠强中毒患者,观察组14例、对照组13例,对照组采用序贯性活性炭血液灌流(HP)方法治疗,观察组采用HP及连续性静脉-静脉血液滤过(CVVH),即序贯性血液净化的方法进行治疗。结果经治疗后,两组患者临床疗效对比具有显著性差异(P<0.05),临床症状改善时间对比具有显著性差异(P<0.05)。结论采用CVVH是较为有效的清除毒鼠强的方法,但应注意的是,采用CVVH治疗的方法应及早进行。
Objective To observe the clinical efficacy of sequential blood purification in the treatment of severe tetramine poisoning. Methods Twenty-seven patients with severe tetramine poisoning were selected in our hospital. The observation group was 14 cases and the control group was 13 cases. The control group was treated by sequential activated carbon hemoperfusion (HP). The observation group was treated with HP and continuous veno-venous blood Filtration (CVVH), a method of sequential blood purification. Results After treatment, there was significant difference between the two groups in clinical curative effect (P <0.05) and in clinical symptom improvement time (P <0.05). Conclusions The use of CVVH is a more effective method of removing tetramine, but it should be noted that the treatment with CVVH should be performed as soon as possible.