病毒与细胞表面分子结合是病毒感染的前提。研究丙型肝炎病毒(HCV)感染细胞的相关分子,对于阐明HCV的感染机制、预防和治疗丙型肝炎以及建立感染模型具有重要意义。近年来,该方面研究取得了一些重要进展,几种能介导病毒感染的细胞分子被相继发现,如低密度脂蛋白受体(LDLr)、CD81、GAGs和Sip-L等。本文旨在对这些细胞分子作一综述。 Virus and cell surface molecule binding is a prerequisite for viral infection. Studying the related molecules of Hepatitis C virus (HCV) infected cells is of great significance to clarify the mechanism of HCV infection, prevent and treat Hepatitis C and establish an infection model. In recent years, some important progress has been made in this aspect. Several cell molecules that can mediate virus infection have been successively discovered, such as LDL, CD81, GAGs and Sip-L. This article aims to give an overview of these cellular molecules.