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妊娠高血压(PIH)的围产期死亡率与高血压病的严重程度有直接关系。如能做到 PIH 的早期诊断和防止其发展到妊娠晚期的严重阶段,将能改善胎儿和新生儿的生存率。本文对599例初期血压正常的单胎孕妇,无肾病史,闭经前16周每月以仰卧位测量血压,并仔细追查研究血压变化,PIH 的发展,蛋白尿和胎儿的结果。根据 Burton 氏公式MAP=(收缩压+2舒张压)/3mmHg以第5和第6个月所有血压记录的平均值计算出平均动脉压(MAP_2)。PIH 的诊断是根据美国产母福利会的标准。蛋白尿是以常规定性煮沸法用1-4个“+”号表示。胎儿宫内发育迟缓(IUGR)的诊断是依据作者医院儿科制定的孕期胎儿增长表,出生体重低于其妊娠期平均体重的1个标准差来决定。研究对象中初产妇占53.38%,第二胎24%,第三胎15.59%,第四胎及以上6.84%,年龄为19-36岁。
Perinatal mortality in gestational hypertension (PIH) is directly related to the severity of hypertension. Early detection of PIH and prevention of its progression to severe stages of late pregnancy will improve fetal and neonatal survival rates. In this paper, 599 cases of singleton fetus with normotensive blood pressure without previous history of nephropathy and 16 weeks before amenorrhea were measured blood pressure in supine position every month. Careful tracing of blood pressure, PIH development, proteinuria and fetus results were performed. Mean arterial pressure (MAP_2) was calculated as the mean of all blood pressures recorded at the 5th and 6th months according to Burton’s formula MAP = (systolic blood pressure + 2 diastolic blood pressure) / 3 mmHg. The diagnosis of PIH is based on the standards of the American Welfare Society. Proteinuria is a routine qualitative boiling with 1-4 “+” sign. The diagnosis of intrauterine growth retardation (IUGR) is based on a table of fetal growth during pregnancy defined by the author’s hospital pediatrician, with a birth weight less than one standard deviation of its average gestational weight. The study object accounted for 53.38% of primipara, 24% of the second child, the third child 15.59%, the fourth child and above 6.84%, aged 19-36 years old.