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72例超重或肥胖者根据血脂水平分成32例高脂血症组和40例对照组,分别测定血清leptin、Fins、ln(HomaIR)、BM1、腰臀比(WHR)、血E2、游离睾酮,并选取54例正常体重者根据血脂水平分成26例高脂血症患者和28例正常对照组,同样分别测定,观察之间的关系。结果:超重或肥胖组Fins、血清leptin水平明显升高,血清leptin水平有明显的性别差异,男:女约为1:3.4。leptin与血脂无明显相关(P>0.05)Fins、IR值(P<0.05)与血脂显著相关(P<0.05)。leptin值与BMI、WHR、Fins(P<0.05)相关,与IR值无明显相关(P>0.05)。结论:血脂紊乱与Fins、IR值相关,血清leptin水平有明显的性别差异,leptin与血脂无明显相关。
72 cases of overweight or obese were divided into 32 cases of hyperlipidemia group and 40 cases of control group according to the level of serum lipids. Serum leptin, Fins, ln (HomaIR), BM1, WHR, E2, free testosterone, 54 healthy people were divided into 26 cases of hyperlipidemia and 28 cases of normal control group according to the level of serum lipids, and the same were respectively measured and observed. Results: The level of leptin in Fins and overweight or obese group was significantly increased, and the level of leptin in serum was significantly different. The male to female ratio was 1: 3.4. There was no significant correlation between leptin and lipids (P> 0.05), Fins, IR (P <0.05), and serum lipid (P <0.05). Leptin values were correlated with BMI, WHR, Fins (P <0.05), but not with IR (P> 0.05). Conclusion: The dyslipidemia is related to the Fins and IR, the serum leptin level has obvious gender difference, leptin has no obvious correlation with the blood fat.