经唇下、粘膜下、鼻中隔、蝶窦切除脑垂体瘤系本世纪初 Cushing 在前人的基础上创建的。当时开颅切除垂体瘤死亡率高达70～80%,Cush-ing 用此术式切除垂体瘤231例,其手术死亡率降至2.5%。但是这种手术开口小、手术部位深、照明不够,以致手术不彻底、复发率高。随着神经外科技术进步,开颅死亡率已降低,且直视下对视神经减压较好,故多采用经额开颅切除垂体瘤,一直延 Subcutaneously, submucosally, nasal septum, sphenoid resection pituitary tumor at the beginning of this century Cushing created on the basis of the predecessor. At that time craniotomy resection of pituitary tumor mortality rate as high as 70 to 80%, Cush-ing with this surgical resection of pituitary tumor in 231 cases, the operative mortality rate dropped to 2.5%. However, this small opening surgery, surgical site deep, inadequate lighting, resulting in incomplete surgery, high recurrence rate. With the progress of neurosurgery, craniotomy mortality has been reduced, and under direct vision decompression of the optic nerve is better, so the use of craniotomy for extracranial tumors, has been extension