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目的 对肝得宁片中的齐墩果酸进行含量测定。方法 基于小波变换的时频局部化性质 ,通过对色谱重叠峰信号小波变换后的某些频率段进行放大 ,使重叠峰得到了分离。结果 齐墩果酸从重叠峰中得到分离 ,取得令人满意的定量分析结果。结论 小波变换能够降低色谱分离条件的要求 ,提高检测准确度。化学计量学解析法与HPLC相结合将为复杂中药分析提供一种全新手段
Objective To determine the content of oleanolic acid in Gandening tablets. Methods Based on the time-frequency localization properties of wavelet transform, the overlapping peaks were separated by amplifying the frequency bands after the wavelet transform of overlapping peaks. Results Oleanolic acid was separated from the overlapping peaks and satisfactory quantitative analysis results were obtained. Conclusion Wavelet transform can reduce the requirements of chromatographic separation conditions and improve detection accuracy. The combination of chemometric analytical method and HPLC will provide a brand new method for the analysis of complex Chinese medicine