Tetracycline(TC)is an antibiotic mainly used in livestock production and respiratory infection.Traditional methods are not effective in removing TC from solution.In this study,TC was degraded by gas-liquid plasma in the presence of rGO-TiO2 in solution.The rGO-TiO2 was prepared by modified hummers and hydrothermal method.The electrical and optical properties of the gas-liquid discharge plasma were studied and the produced long-lived reactive species were analyzed by spectrophotometer.The degradation efficiency of TC was improved by 41.4％after plasma treatment for 12 min in presence of 30 mg l-1 rGO-TiO2 compared to that with plasma alone.The degradation efficiency increased with increasing discharge power,but as the initial concentration was increased from 20 to 80 mg l-1,the degradation efficiency of TC decreased.The initial pH had no significant effect on the degradation of TC.The intermediate products were determined by UV-vis spectrophotometry and ESI(+)-MS,and the degradation mechanism was analyzed.The reactive species,including O3,OH,and H2O2,etc.,produced in the plasma/catalyst system attracted electron-rich functional groups(amino group,aromatic ring,and double bond).Therefore,the gas-liquid plasma/catalyst system could be an effective and promising method for pharmaceutical wastewater treatment in future.