手术治疗鼻窦癌有一定困难,其主要影响因素是手术切缘常常有肿瘤阳性组织。本文研究的主要目的是评价颅底手术对获得无瘤边缘对疾病控制的影响。对50例鼻窦癌病人采用颅底手术治疗,进行了回顾性总结,手术方式包括首次手术和二次对复发性疾病的补救性手术,其中多半是补救性手术,在平均40个月的随访中,成活率是74％,64％的病人无瘤生存(NED)或死于其它疾病(DOC)。 Surgical treatment of sinus cancer has some difficulties, the main factors that affect the surgical margins are often tumor-positive tissue. The main purpose of this study is to evaluate the effect of skull base surgery on the control of disease-free margins. Fifty cases of sinus cancer patients treated with skull base surgery were reviewed retrospectively, including the first and second surgical procedures for recurrent disease, salvage surgery, most of them are remedial surgery, with an average follow-up of 40 months , Survival rate was 74%, 64% of patients with tumor-free survival (NED) or died of other diseases (DOC).