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目的观察缬沙坦分散片联合雷公藤多苷治疗糖尿病肾病蛋白尿的临床效果。方法选择我院2009年9月至2010年12月就诊的2型糖尿病肾病患者85例,遵照知情同意原则并按照随机数字表法分为两组,对照组42例采用常规治疗,观察组43例采用缬沙坦分散片联合雷公藤多苷治疗,比较两组的临床应用情况。结果观察组的总有效率为97.7%,略高于对照组的95.2%,两组间差异无统计学意义(P>0.05);观察组治疗后24h尿蛋白定量、尿微量白蛋白均明显低于对照组,组间差异有统计学意义(P<0.05)。结论缬沙坦分散片联合雷公藤多苷治疗糖尿病肾病蛋白尿的临床满意,能更好地降低糖尿病肾病患者蛋白尿水平,保护患者的肾脏功能。
Objective To observe the clinical effect of valsartan dispersible tablets combined with tripterygium glycosides in the treatment of diabetic nephropathy proteinuria. Methods Eighty-five patients with type 2 diabetic nephropathy treated in our hospital from September 2009 to December 2010 were selected and divided into two groups according to the principle of informed consent and according to the random number table. Forty-two patients in the control group received routine treatment and 43 patients in the observation group Valsartan dispersible tablets combined with Tripterygium glycosides treatment, clinical application of the two groups were compared. Results The total effective rate in the observation group was 97.7%, slightly higher than that in the control group (95.2%), with no significant difference between the two groups (P> 0.05). Urine proteinuria and urinary albumin in the observation group were significantly lower In the control group, the difference between the groups was statistically significant (P <0.05). Conclusion Valsartan dispersible tablets combined with tripterygium glycosides in the treatment of diabetic nephropathy proteinuria clinical satisfaction, can better reduce proteinuria in patients with diabetic nephropathy, to protect the patient’s renal function.