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为了观察中药组方溶宁制剂对小鼠急性溶血性贫血的治疗效果,以及对溶血性贫血小鼠外周血象和肝脏、脾脏的影响,试验采用外周血象观测、组织制片技术、免疫荧光及透射电镜观察等方法对其进行了研究。结果表明:中药组方溶宁能改善外周循环血及肝脏、脾脏中细胞的超微结构,以及PCNA抗原、Hochest 33258在细胞核上的表达。说明溶宁制剂对溶血性贫血有一定防治效果。
In order to observe the therapeutic effect of Fangningning Preparation on acute hemolytic anemia in mice and its effect on peripheral blood and liver and spleen of mice with hemolytic anemia, the peripheral blood hemodynamics, tissue preparation technique, immunofluorescence and transmission Electron microscopy and other methods were studied. The results showed that the traditional Chinese medicine Fanglinning can improve the peripheral blood and liver, spleen in the cell ultrastructure, and PCNA antigen, Hochest 33258 in the nucleus. Explain that Rong Ning preparation has a certain control effect on hemolytic anemia.