他巴唑是治疗甲亢最常用的药物 ,但会引起少数患者粒细胞缺乏 (下称粒缺 ) ,其预后严重 ,必须积极治疗。本文对 1995～ 1999年 13例住院患者的临床资料及治疗情况进行分析讨论。临床资料　诊断均符合甲亢的通行诊断标准 ,合并粒细胞缺乏 ,其粒细胞绝对值 0 5× 10 9/Ｌ。本组 Methimazole is the most commonly used drug for the treatment of hyperthyroidism, but will cause a small number of patients with neutropenia (hereinafter referred to as granuloma), the prognosis is serious and must be actively treated. This article from 1995 to 1999, 13 cases of hospitalized patients with clinical data and treatment were analyzed and discussed. Clinical data were diagnosed in line with the prevalence of hyperthyroidism diagnostic criteria, combined with agranulocytosis, the absolute value of granulocytes 0 5 × 10 9 / L. This group