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目的探讨喹诺酮类药物对治疗沙门氏菌感染的临床治疗效果。方法 214例因沙门氏菌感染导致腹泻的患者随机分成对照组与观察组,各107例。对照组给予氨苄青霉素和思密达治疗,观察组给予喹诺酮类盐酸左氧氟沙星治疗,对两组患者的治疗效果和不良反应进行观察。结果观察组治疗有效率100.0%,对照组治疗有效率78.5%,两组比较差异有统计学意义(P<0.05);观察组无任何不良反应发生,对照组不良反应发生率为6.5%,两组比较差异有统计学意义(P<0.05)。结论喹诺酮类药物治疗沙门氏菌感染疗效显著,值得在临床上推广应用。
Objective To investigate the clinical effect of quinolones in the treatment of Salmonella infection. Methods A total of 214 patients with diarrhea due to Salmonella infection were randomly divided into control group and observation group, with 107 cases in each group. The control group was given ampicillin and Smectite treatment, the observation group was given quinolone levofloxacin hydrochloride treatment, the two groups of patients with treatment and adverse reactions were observed. Results The effective rate of treatment in the observation group was 100.0%, while that in the control group was 78.5%, there was significant difference between the two groups (P <0.05). There was no adverse reaction in the observation group and the incidence of adverse reactions in the control group was 6.5% The difference was statistically significant (P <0.05). Conclusion Quinolones treatment of Salmonella infection significant effect, it is worth in the clinical application.