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目的:探讨儿童阻塞性睡眠呼吸暂停低通气综合征(OSAHS)而致的低氧血症对听功能的影响。方法:对OSAHS患儿鼓室导抗图为“A”型的68耳进行听性脑干反应(ABR)监测,60耳行畸变产物耳声发射(DPOAE)监测,并与正常儿童30耳(对照组)进行比较。结果:轻度OSAHS患儿ABR各波潜伏期和波间期与对照组比较,均差异无统计学意义(均P>0.05);中重度OSAHS患儿Ⅰ波潜伏期延长,与对照组比较,差异有统计学意义(P<0.05),各波间期与对照组比较,均差异无统计学意义(均P>0.05)。轻度OSAHS患儿的DPOAE幅值在8kHz下降,与对照组比较差异有统计学意义(P<0.05);中重度OSAHS患儿的DPOAE幅值在6kHz和8kHz下降,与对照组比较均差异有统计学意义(均P<0.05)。结论:ABR和DPOAE可监测AHI≥10次/h的OSAHS患儿听功能的早期损害。
Objective: To investigate the effect of hypoxemia on hearing function in children with obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods: The auditory brainstem response (ABR) was monitored in 68 tympanograms of tympanograms of OSAHS patients, and 60 ears were measured by the product of otoacoustic emissions (DPOAE). The results were compared with those of normal children (Control group) for comparison. Results: Compared with the control group, there was no significant difference in the latency and wave interval of ABR among children with mild OSAHS (all P> 0.05). The latency of Ⅰ wave in children with moderate-severe OSAHS was longer than that of the control group Statistical significance (P <0.05). There was no significant difference between each wave interval and control group (P> 0.05). The DPOAE amplitude of children with mild OSAHS decreased at 8kHz, the difference was statistically significant compared with the control group (P <0.05); the DPOAE amplitude of children with moderate-severe OSAHS decreased at 6kHz and 8kHz, compared with the control group Statistical significance (all P <0.05). Conclusion: ABR and DPOAE can monitor early hearing loss in OSAHS children with AHI ≥10 beats / h.