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目的 探讨磁共振成像(MRI)对前列腺癌分期和病理对照的临床意义。方法 对30例病理证实的局限性前列腺癌行术前MRI分期,并以此预测前列腺癌根治术后的病理分期结果,评价诊断性实验结果。结果 本组30例前列腺癌中,MRI分期局限于前列腺内的肿瘤(B期)21例,4例术后病理报告为C期,19.1%(4/21)的病例MRI分期偏低,9例C期病例1例术后为B期,分期偏高,另1例术后为D期,分期偏低。MRI分期对局限于前列腺内肿瘤的阳性预测(PPV)为80.9%;对浸润包膜及包膜外肿瘤的阴性预测(NPV)为88.9%。MRI对前列腺癌病理分期的预测更具有特异性和较高的准确性,能更好地预测前列腺癌的病理结果(x2=3.145,P=0.023)。结论 MRI能更好地预测局限于前列腺内的肿瘤,对前列腺包膜及包膜以外浸润的肿瘤能进行更准确的分期。
Objective To investigate the clinical significance of magnetic resonance imaging (MRI) in staging and pathological comparison of prostate cancer. Methods Preoperative MRI staging was performed on 30 pathologically confirmed localized prostate cancers. Based on this, the pathological staging results after radical prostatectomy were evaluated, and the diagnostic test results were evaluated. Results In the group of 30 cases of prostate cancer, MRI staging was limited to 21 cases of prostate cancer (stage B), 4 cases of postoperative pathology were C stage, 19.1% (4/21) had lower MRI stage and 9 cases One case of stage C was stage B after operation, the stage was high, and the other one was stage D after operation. The stage was low. The positive predictive value (PPV) for tumor localized to the prostate was 80.9% for MRI staging and 88.9% for negative and invasive envelopes. MRI is more specific and accurate in predicting the pathological stage of prostate cancer, and can better predict the pathological findings of prostate cancer (x2 = 3.145, P = 0.023). Conclusion MRI is better able to predict tumors confined to the prostate and to more accurately stage prostate and extramembranous tumors.