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目的评价康艾注射液辅助化学疗法(化疗)对直肠癌术后临床疗效、生活质量及其不良反应的影响。方法 2010年4月-2011年2月收治的50例直肠癌术后化疗患者,随机分为试验组与对照组,每组25例。两组均采用FOLFOX方案化疗,在化疗同时,试验组予静脉滴注康艾注射液辅助治疗。连续治疗6个周期,比较两组临床疗效、生活质量及其不良反应情况。结果试验组治疗有效率为84%,对照组为88%,差异无统计学意义(P>0.05);两组生活质量改善率差异无统计学意义(P>0.05);试验组胃肠道反应、白细胞计数下降发生率低于对照组,差异有统计学意义(P<0.05)。结论康艾注射液用于直肠癌术后的辅助化疗可降低化疗的不良反应。
Objective To evaluate the effect of Kangai injection adjuvant chemotherapy (chemotherapy) on postoperative clinical efficacy, quality of life and adverse reactions of rectal cancer. Methods From April 2010 to February 2011, 50 patients with postoperative chemotherapy for rectal cancer were randomly divided into test group and control group, with 25 cases in each group. Both groups were treated with FOLFOX regimen. At the same time of chemotherapy, the experimental group was given intravenous drip Kangai injection adjuvant therapy. Continuous treatment of 6 cycles, the two groups were compared clinical efficacy, quality of life and adverse reactions. Results The effective rate of treatment was 84% in the trial group and 88% in the control group, with no significant difference (P> 0.05). There was no significant difference in the quality of life between the two groups (P> 0.05). The gastrointestinal reaction , The incidence of white blood cell count decreased lower than the control group, the difference was statistically significant (P <0.05). Conclusions Kangai injection for postoperative adjuvant chemotherapy of rectal cancer can reduce the adverse reactions of chemotherapy.