1 为什么肾脏易遭受药物性损害第一 ,肾血流量丰富。肾的重量仅为人体重的0 5 %～ 1 % ,而从心脏搏出血液的大约 2 0 %～ 3 0 %流入肾脏 ,致使肾脏曝露于大量的药物之下。第二 ,肾具有尿浓缩功能 ,肾小球滤过的原尿随着水分的吸收而在肾脏被高度浓缩。第三 ,近曲小管存在药物 1 Why the kidney vulnerable to drug-induced damage First, rich in renal blood flow. The weight of the kidneys is only 0.5% to 1% of the body weight, and about 20% to 30% of the blood is pumped into the kidneys from the heart, leaving the kidneys exposed to a large amount of medication. Second, the kidney has the function of urinary concentration, glomerular filtration of the original urine with the absorption of water in the kidney is highly concentrated. Third, there is drug in the proximal convoluted tubule