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目的通过肺成熟度预测对可能发生新生儿呼吸窘迫综合征的早产儿进行积极预防,同时避免部分早产儿不必要的气管插管及PS使用。方法对136例正常新生儿及早产儿进行板层小体计数,尝试找出反应肺成熟度的不成熟判定界值和成熟判定界值,并统计其对肺成熟度的阳性预测值、阴性预测值、敏感性、特异性,以避免部分早产儿不必要的气管插管及PS的使用。结果成熟判定界值≥98000/uL时其阴性预测值100%;阳性预测值17.4%;敏感性100%;特异性36.7%;不成熟判定界值≤33000/uL时阴性预测值98%;阳性预测值36.8%;敏感性87.5%;特异性81.7%。
Objective To predict the extent of lung maturity in premature infants with respiratory distress syndrome and to prevent unnecessary preemptive tracheal intubation and PS administration in some premature infants. Methods The platelet bodies of 136 normal newborns and premature infants were enumerated. The immature judgment threshold and mature judgment threshold of response lung maturation were attempted, and the positive predictive value, negative predictive value , Sensitivity and specificity to avoid unnecessary tracheal intubation and PS use in some premature infants. RESULTS: The negative predictive value was 100% when the cutoff value was ≥ 98000 / uL; the positive predictive value was 17.4%; the sensitivity was 100%; the specificity was 36.7%; the immature cutoff value was ≤33000 / uL, the negative predictive value was 98% Predicted value 36.8%; Sensitivity 87.5%; Specificity 81.7%.