在哺乳动物中,缺氧导致肺血管收缩是一种基本的反射。长期以为,认为此现象具有两种主要的生理功能。在胎儿时期,其作用为关闭肺循环,以避免血液由于分流而通过未通气的肺组织。出生以后,其作用为确保灌注和通气比例的恒定。问题在于当肺面临着由于高原或慢性缺氧性肺病所致的普遍性缺氧时。该反射似成为恶性,并引起肺动脉高压。故这种反射对人类是否有益,似为一个疑问。慢性缺氧性肺病的病人均有发生肺动脉高压有危险,有作者指出该类病人的肺动脉高压是与其 In mammals, hypoxia leads to pulmonary vasoconstriction as a basic reflection. Long thought that this phenomenon has two main physiological functions. In fetal times, its role is to turn off the pulmonary circulation to prevent blood from passing through the non-ventilated lung tissue as a result of shunting. After birth, its role is to ensure constant perfusion and ventilation rates. The problem is when the lungs face a generalized lack of oxygen due to altitude sickness or chronic hypoxic lung disease. The reflex seems to be malignant and cause pulmonary hypertension. Therefore, this reflex is beneficial to humans, it seems to be a doubt. Patients with chronic hypoxic pulmonary disease are at risk of pulmonary hypertension, the authors pointed out that such patients with pulmonary hypertension is