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原发性肝癌(简称肝癌)是亚非地区常见而预后极差的癌症。由于症状隐匿,难以早期发现。国际文献中,小于5厘米的小肝癌罕见报导。1975年Okuda等曾有报导,到1977年共报告20例,其中16例为尸体解剖所见,仅4例系临床发现。甲胎蛋白(AFP)应用于临床检测以来,肝癌的诊断水平有所提高。而Cameron等认为:“AFP是有用的诊断工具,但未能达到足以改善疗效的早期诊断,作为普查的汗力亦有限。”本文报告23例AFP普查发现的小肝癌和7例临床发现的小肝癌,分析其治疗与预后,并对AFP在普查巾早期诊断的价值和早期治疗对预后的影响作了探讨。
Primary liver cancer (abbreviated as liver cancer) is a cancer that is common in Asia and Africa and has a very poor prognosis. Due to the hidden symptoms, it is difficult to find early. In the international literature, small HCCs less than 5 cm are rarely reported. In 1975 Okuda et al reported that 20 cases were reported in 1977, of which 16 cases were seen by autopsy and only 4 cases were clinical findings. Alpha-fetoprotein (AFP) has been used clinically to improve the diagnostic level of liver cancer. Cameron et al. argued that “AFP is a useful diagnostic tool, but it failed to achieve early diagnosis to improve efficacy, and limited sweating capacity as a census.” This article reports the small APA census found in 23 cases and 7 cases of clinically discovered small Liver cancer, analysis of its treatment and prognosis, and the value of AFP in the early diagnosis of the census towel and the impact of early treatment on the prognosis were discussed.