Concrete creep under both static and cyclic loading conditions was investigated. Four groups of high-strength high-performance concrete (HSHPC) prism specimens were fabricated, and three of these specimens were loaded periodically by the MTS Landmark Fatigue Testing Machine System. Creep characteristics and creep coefficients of HSHPC under static loading and cyclic loading, respectively, were obtained and compared. The experimental results show that the creep strains under cyclic loading with a mean stress of 0.4 fcp and an amplitude of 0.2 fcp increase significantly compared with the creep strains under static loading, and the maximum value was 1.2-2.3 times at early stages. In addition, the creep coefficient increases nonlinearly with the number of cyclic loading repetitions. The influence coefficient for cyclic loadingγcyc=1.088×(N/N0)0.078 was introduced based on the previous HSHPC creep model, and then the modified creep model under cyclic loading was established. Finally, the residual method, the CEB coefficient of variation method and the B3 coefficient of variation method were applied to evaluate the modified creep model. The statistical results demonstrate that the modified creep model agrees well with the experimental measurements. Hence, it has important theoretical and practical values for accurately predicting the deflection of concrete bridges under cyclic traffic loading.