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成年脑组织含有多聚腺苷酸化(poly(A)~+)和非多聚腺苷酸化(poly (A)~-)的复杂mRNA群.这些mRNA彼此不同,但在复杂程度上相似。整个脑组织含有约150,000个多核糖体RNA片段,每个片段长约1500个核苷酸.在生物学上,这与脑组织的广泛异质性和不同细胞的微分化是相一致的.相对于绝大多数其它器官来说,出生后脑组织的发育更广泛和精细.为了弄清作为成年脑组织特点的复杂mRNA群是否在出生时就已存在,以及研究出生后脑发育过程中的基因表达,作者用小鼠作
Adult brain tissue contains a complex set of polyadenylated (poly (A) ~ +) and non-polyadenylated (poly (A) ~) mRNAs that differ from each other but are similar in complexity. The entire brain tissue contains about 150,000 polysribose RNA fragments, each about 1500 nucleotides in length, which is biologically consistent with the extensive heterogeneity of brain tissue and the differentiation of different cells.Relative In most other organs, the development of brain tissue after birth is more extensive and elaborate.To find out whether complex mRNA pools, which are characteristic of adult brain tissue, are present at birth and to study gene expression during postnatal brain development, The author used mice for