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抗痨肼属于异菸肼油脂系族衍化物,其化学名氰乙醯肼(Cyanacetic acid Hyarazide),簡称C.A.H.实驗証明在試管及动物試驗中,均有抑制結核菌作用。在临床治疗肺結核有一定疗效。其副作用有恶心呕吐,食欲不振,腹痛,麻疹,感觉异常,精神过敏以及类似中毒性精神病等。对糖尿是否会产生不良作用,国內似未見报道。我院一例糖尿病合併肺结核应用抗痨肼治疗,不仅糖尿病控制困难,且肺結核亦发生恶化,茲报道于下:
Isoniazid belongs to the family of isoniazid oil derivatives, its chemical name Cyanacetic acid Hyarazide (C.A.H.) Experiments show that in vitro and animal experiments, have inhibited the role of TB. In clinical treatment of tuberculosis have a certain effect. The side effects of nausea and vomiting, loss of appetite, abdominal pain, measles, sensory abnormalities, mental disorders and similar toxic psychosis. Diabetes whether it will have an adverse effect, the country seems to have not been reported. A case of diabetes mellitus and tuberculosis in patients with anti-tuberculosis treatment, not only difficult to control diabetes, and tuberculosis also worsened, it is reported in the next: