子痫前期的发生率约为3%~5%。其病理生理机制可能包括母亲和胎儿/胎盘因素。胎盘血管在孕早期的发育异常可能导致胎盘灌注不足,缺氧或缺血。然而,子痫前期背后的分子机制尚不清楚。治疗上尚无控制其发生、发展的最佳方法,终止妊娠是治疗子痫前期的唯一有效方法,故早期预测及预防显得尤为重要。1子痫前期的预测1.1临床评估子痫前期只在妊娠期发生。导致子痫前期的相关危险因素包括子痫前期的家族史、初产 The incidence of preeclampsia is about 3% to 5%. Its pathophysiological mechanisms may include maternal and fetal / placental factors. Abnormal placental vascular development in early pregnancy may lead to inadequate placental perfusion, hypoxia or ischemia. However, the molecular mechanism underlying preeclampsia is not clear. There is no treatment for its occurrence and development of the best method of termination of pregnancy is the only effective treatment of preeclampsia, so early prediction and prevention is particularly important. 1 Predictors of preeclampsia 1.1 Clinical assessment of preeclampsia occurs only during pregnancy. The associated risk factors leading to preeclampsia include a family history of preeclampsia, primiparous