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目的分析不同空腹血糖水平冠心病患者的临床特征和冠脉造影特点。方法 106例经冠脉造影确诊的冠心病患者根据FPG水平分为三组:正常空腹血糖(NFG)组60例,FPG<5.6mmol/L;空腹血糖受损(IFG)组1 6例,FPG5.6～7.0mmol/L;糖尿病(DM)组30例,FPG>7.0mmol/L。测量血压和FPG、血脂、肌酐等生化指标,比较三组患者的临床和冠状动脉造影特点。结果 (1)三组间年龄、冠心病病程、TC、TG、肌酐无统计学差异。自NFG、IFG到DM组,LDL-C逐渐上升,而HDL-C逐渐下降,组间比较差异有统计学意义(P<0.05)。(2)随着FPG水平上升,冠状动脉重度狭窄、完全闭塞和弥漫性病变比例增高,T2DM冠心病组发生3支病变较多(P<0.05),发生率为40%。结论随着FPG上升,冠状动脉病变严重程度加重,FPG水平升高是发生冠心病的危险因素。
Objective To analyze the clinical characteristics and coronary angiography features of coronary heart disease patients with different fasting blood glucose levels. Methods One hundred and six patients with coronary heart disease diagnosed by coronary angiography were divided into three groups according to FPG levels: 60 cases in normal fasting glucose group (FPG <5.6mmol / L), 16 cases in fasting glucose impaired group (IFG), FPG5 .6 ~ 7.0mmol / L, diabetic group (DM) 30cases, FPG> 7.0mmol / L. Measurement of blood pressure and FPG, blood lipids, creatinine and other biochemical indicators, clinical and coronary angiographic characteristics of three groups were compared. Results (1) There was no significant difference in age, duration of coronary heart disease, TC, TG and creatinine between the three groups. From NFG, IFG to DM group, the level of LDL-C increased gradually, while the level of HDL-C decreased gradually. The difference between the two groups was statistically significant (P <0.05). (2) With the increase of FPG level, severe coronary stenosis, the ratio of complete occlusion and diffuse lesions increased, and 3 lesions occurred in T2DM coronary heart disease group (P <0.05), the incidence was 40%. Conclusion With the increase of FPG, the severity of coronary artery disease is aggravated. The level of FPG is the risk factor of coronary heart disease.