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目的 探讨支气管 肺泡灌洗 (BAL)对肺生理功能的影响。方法 对 42例间质性肺疾病 (实验组 )灌洗前和灌洗后进行肺功能和动脉血气检测 ,并与 7例无肺疾病非吸烟者做对照 (对照组 )。结果 实验组肺活量占预计值百分比 (VC % )由灌洗前的 (74± 17) % ,下降到灌洗后 (6 4±19) %。一秒钟用力呼气容积占预计值百分比 (FEV1% )由 (72± 9) %下降到 (6 5± 12 ) %。动脉血氧分压 (PaO2 )由 (77± 11)mmHg下降到 (6 3± 11)mmHg。对照组灌洗后上述指标虽有所下降 ,但统计学分析差异无显著性。结论 BAL对间质性肺疾病患者的肺功能和动脉血气有一定影响
Objective To investigate the effects of bronchoalveolar lavage (BAL) on lung function. Methods Twenty - four patients with interstitial lung disease (experimental group) were tested for pulmonary function and arterial blood gas before and after lavage, and compared with 7 non - smokers without lung disease (control group). Results The percentage of predicted vital capacity (VC%) in experimental group decreased from (74 ± 17)% before lavage to (64 ± 19)% after lavage. The ratio of forced expiratory volume to predicted value (FEV1%) decreased from (72 ± 9)% to (65 ± 12)% in one second. PaO2 decreased from (77 ± 11) mmHg to (6 3 ± 11) mmHg. Although the control group after lavage the above indicators have declined, but the statistical analysis showed no significant difference. Conclusion BAL has some effects on pulmonary function and arterial blood gas in patients with interstitial lung disease