目的　探索脊柱原发性肿瘤的诊治特点。方法　对收治 2 2例原发性脊柱肿瘤临床特点、影像改变 ,外科治疗与介入治疗的选择、疗效进行分析 ,评估。结果　脊柱原发性肿瘤病程漫长 ,缺乏特有临床特征 ,往往呈现明显的脊髓压迫症状才获得诊治 ;CT、MRI检查有助于早期诊断 ;13例较局限椎体肿瘤作全部切除 ,5例较广泛肿瘤作了局部切除 ;有效的内固定是维持脊柱稳定必备的手段。结论　高清晰影像检查 ,有助于原发性脊柱肿瘤早期诊断及手术方式的选择 ;有效手术切除、充分手术减压 ,有利于受压脊髓的恢复 ;手术附加介入治疗 ,能增加手术安全性与成功率 ,减少复发率 ;本组病例总结也为脊柱肿瘤诊断、治疗提供有益经验 Objective To explore the characteristics of diagnosis and treatment of primary tumor of the spine. Methods The clinical features and imaging changes of 22 patients with primary spinal tumors, and the choices and therapeutic effects of surgical treatment and interventional treatment were analyzed and evaluated. Results The primary tumor of the spine had a long duration and lacked unique clinical features. It often showed obvious symptoms of spinal cord compression before diagnosis and treatment. CT and MRI examinations were helpful for early diagnosis; 13 cases were more than limited vertebral body tumors for total resection and 5 cases were more extensive. The tumor was locally resected; effective internal fixation is a necessary means to maintain stability in the spine. Conclusion High-resolution imaging is helpful for the early diagnosis of primary spinal tumors and the choice of surgical methods. Effective surgical resection and adequate surgical decompression are beneficial to the recovery of compressed spinal cord. Additional interventional therapy can increase the safety of surgery. Success rate, reduce the recurrence rate; this group of cases also provides useful experience for the diagnosis and treatment of spinal tumors